GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs965513 | 1 | rs1443438 | chr9:100550028 | CLDN2 | chrX:106143394-106174091:+ | 0.26 | 6.08 | 2.48E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1443438 | chr9:100550028 | EFNB2 | chr13:107142098-107187337:- | -0.25 | -5.87 | 7.95E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1443438 | chr9:100550028 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.83 | 2.65E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1443438 | chr9:100550028 | EPDR1 | chr7:37960163-37991539:+ | 0.32 | 7.23 | 1.88E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1443438 | chr9:100550028 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.61 | 1.08E-16 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1443438 | chr9:100550028 | PLCE1 | chr10:95753746-96088146:+ | 0.26 | 5.99 | 4.14E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1443438 | chr9:100550028 | TTC8 | chr14:89290497-89344334:+ | 0.24 | 6 | 3.88E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs1056667 | 1 | rs1535277 | chr6:26567802 | ZNF322B | chr9:99957633-99961910:- | 0.59 | 11.41 | 7.49E-27 | Educational attainment |
| THCA | trans | rs965513 | 1 | rs1561962 | chr9:100546219 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.26 | 8.41E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1561962 | chr9:100546219 | CLDN2 | chrX:106143394-106174091:+ | 0.27 | 6.17 | 1.48E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1561962 | chr9:100546219 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.97 | 1.07E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1561962 | chr9:100546219 | EPDR1 | chr7:37960163-37991539:+ | 0.32 | 7.15 | 3.25E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1561962 | chr9:100546219 | GGT5 | chr22:24615623-24641110:- | 0.27 | 6.18 | 1.35E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1561962 | chr9:100546219 | LRRC42 | chr1:54412037-54433839:+ | -0.24 | -6.2 | 1.24E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs1561962 | chr9:100546219 | NKX6-1 | chr4:85414436-85419387:- | 0.49 | 8.65 | 8.04E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |